A paper written by NAKAGAMI Yuki Faculty of Data Science and others (Joint research with the Department of Gastroenterology and Oncology, Graduate School of Medicine, Yamaguchi University) was published in an international journal. The journal Experimental and Therapeutic Medicine is published by SPANDIDOS Publications.

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https://www.spandidos-publications.com/10.3892/etm.2024.12608

Paper information　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　

Magazine name: Experimental and Therapeutic Medicine

Title of the paper: Risk factors for infectious complications after gastrectomy in older patients.

Author: MICHIHISA IIDA¹, SHIGERU TAKEDA¹, TSUNENORI YAMAMOTO¹, CHIYO NAKASHIMA¹, MITSUO NISHIYAMA¹, YUSAKU WATANABE¹, YOSHITARO SHINDO¹, YUKIO TOKUMITSU¹, SHINOBU TOMOCHIKA¹, YUKI NAKAGAMI², HIDENORI TAKAHASHI¹ and HIROAKI NAGANO¹

¹Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine

²Department of Data Science, Faculty of Data Science, Shimonoseki City University

Overview of Research　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　

"Purpose": Identify risk factors for infectious complications before and during surgery in elderly patients with gastric cancer.

"Method": For 504 gastric cancer patients aged 65 and over who had undergone radical gastric resection, statistical modeling and cross-checking methods were analyzed based on the Clavien-Dindo classification from preoperative and postoperative factors.

“Results”: Of the 504 patients, 95 (18.8%) had infectious complications. Analysis of preoperative factors alone showed that men and prognosis nutritional indexes were low, visceral fat area values were high, and total gastric resection was a risk factor for complications after gastric resection. Among all the intraoperative factors, prolonged surgery with low prognostic nutritional index values was identified as a risk factor for complications after gastric resection. Furthermore, when patients were divided into five groups according to the number of positive risk factors for preoperative infectious complications, the incidence of complications varies among groups.

"Conclusion": It was found that older patients with gastric cancer need to carefully consider the adaptation of gastric resection, reduce surgical time and reduce complications when high preoperative risk factors are high.

[Published date: 07.03, 2024]