Statistics, Data Science, Health Data Science, Biostatistics, Gastrointestinal Cancer

Management Data Analysis I/II, Liberal Arts Statistics, Specialized Exercise I/II, Academic Literacy PC (faculties)
"Measurement and Quantitative Methodology" (Graduate School)
“Biostatistics”, “Introduction to Clinical Research”, “Statistical Social Survey Method”, “Statistical Social Survey Method”, “DS Project”, “Graduation Research”, “Nursing Informatics” (planned)

2011 Graduated from Doshisha University Faculty of Cultural Informatics
Graduate School of Statistics, Western Michigan University, United States, 2018
2018 Graduate Certificate in Biostatistics, Western Michigan University Graduate School of Statistics, United States
Graduated from the Department of Gastroenterology and Oncology, Yamaguchi University Graduate School of Medicine in 2023

Ph.D. (Medical)
Master of Science (Statistics)
Graduate Certificate (Biostatistics)

International Association of Measuring Biology, Japan Society of Measuring Biology, Japanese Society of Measuring Surgery, Japanese Society of Cancer Therapy, American Statistical Society, Japanese Society of Cancer, Life Intelligence Consortium (LINC)

Statistics, Data Science, Health Data Science, Biostatistics, Natural and Humanities and Social Sciences, R, personalized therapy, bridging research, clinical trials, gastrointestinal cancer, cancer immunity, dimensional shrinkage, classification, SAS, Python, Julia

　We have been conducting research that leads to bridging research and personalized therapy, focusing on statistical consulting for medical research, including application of statistical and data science methods to gastrointestinal cancer research and clinical trials. Utilizing the experience and network of joint research with medical and research institutes, IT/pharmaceutical companies, etc., we are promoting research on the theory culture.
　We also participated in the Life Intelligence Consortium (LINC)*, and are conducting research activities in industry, government, academia, and government as a representative and contributor to joint research such as "Building a nationwide digital health data infrastructure", "Individualizing medication/nutrition guidance", "Cost-benefit analysis of pharmaceuticals using real-world data using electronic medical record information" and "Riku routing efficiency of clinical trial patients".
*All Japan Consortium was established in November 2016 by Kyoto University, RIKEN, Pharmaceutical Infrastructure, Health and Nutrition Research Institute, etc. for the purpose of developing AI and big data in the life sciences related to pharmaceutical, chemical, food, medical, and health care, and incorporated in April 2021.

・The C11orf24 gene as a useful biomarker for predicting severe neutropenia in modified FOLFIRINOX for pancreatic cancer. Gen Kanesada, Ryouichi Tsunedomi, Yuki Nakagami, et al. Cancer Science. 2025.
・High serum proteinase-3 levels predict poor progression-free survival and lower efficacy of bevacizumab in metastatic colorectal cancer. Kei Furuya, Masao Nakajima, Ryouichi Tsunedomi, Yuki Nakagami, Ming Xu, et al. BMC cancer. 2024.
・Clinical outcomes of second‑line chemotherapy after gemcitabine and cisplatin plus S‑1 treatment for patients with advanced biliary tract cancer in the KHBO1401‑3A study. Yoshitaro Shindo, Hiroaki Nagano, Yuki Nakagami, et al. ONCOLOGY REPORTS. 2023.
・CD4 and FOXP3 as predictive markers for the recurrence of T3/T4a stage II colorectal cancer: applying a novel discrete Bayes decision rule. Yuki Nakagami, Shoichi Hazama, Nobuaki Suzuki, et al. BMC Cancer. 2022.
・Viral elimination is essential for improving surgical outcomes of HCV-related HCC: Multicenter retrospective analysis. Masao Nakajima, Shogo Kobayashi, Yuki Nakagami, et al. Annals of Gastroenterological Surgery. 2020. A top cited paper in Annals of Gastroenterological Surgery 2020-2021.
・In 2020, the 33rd Japan Society of Biotherapy Encouragement Award, "Searching for Biomarkers for New Preoperative Peptide Vaccines for Resectable Hepatocellular Carcinoma by Mass Cytometry Analysis and Immunodeficiency Adjuvant Use Cases"
・In 2020, the 41st Cancer Immunology Society Encouragement Award "Immune Reactions of New Preoperative and Postoperative Vaccine Therapy Cases for HCC: Explorative Data Analysis of T Cells by Masscytometry"
・Induction of tumor infiltrating T cells by a novel neoadjuvant vaccine: Analyzing PBMCs and surgical specimens.

・Grant-in-Aid for Scientific Research (Basic Research C) "CyTOF analysis of colon tumor infiltration CD4+FOXP3+ cells and its role as prognosis factor"
・Research representative of the research project "Stage II colon cancer prognostic factors by CyTOF analysis of tumor-invasive immune cells" by young researchers from Yamaguchi University Fund
・Grant-in-Aid for Scientific Research (Basic Research C) "Early Diagnosis for Non-Valous Liver Cancer Using Natural Immune Factors as New Biomarkers"
・Grant-in-Aid for Scientific Research (Basic Research C) "Development of early diagnosis markers for liver cancer associated with lifestyle-related diseases: Analysis of extracellular vesicles in blood"
・Grant for Scientific Research (Basic Research C) "Development of a multi-month life expectancy prediction system for cancer based on in-hospital real-world data"
・Grant-in-Aid for Scientific Research (Basic Research C) "Development of AI to predict pathological progress using real-world data based on electronic medical record information"
・Japan Science and Technology Agency (COI-NEXT)) “Well-being community co-creation base created by a health-based economic development model and a whole-generation approach”

Member of the University League Yamaguchi Data Science Education Working Group
Lectures Okayama Yoshiizumi High School, Shimo Kansai High School (Super Science High School Certified School), Hagi High School, Kitakyusyu High School, Kagoshima Chuo High School (Super Science High School Certified School), Shimonoseki Commercial High School
Japan Hepatobiliary Pancreatic Oncology Network (JON-HBP) Statistical Expert
Kansai Livelihood Onkoroze Group (KHBO) Statistical Expert
Statistical Advisor, National Hospital Organization Kanmon Medical Center
Department of Gastroenterology and Oncology, Graduate School of Medicine, Yamaguchi University Part-time Lecturer and Statistical Expert
Department of Public Health and Preventive Medicine, Graduate School of Medicine, Yamaguchi University

Understanding phenomena, solving problems, and creating value through the approach of data science (data science)

・Take care of your colleagues in the laboratory.
・You can clearly explain your research agenda and research plan in your own words.
・You can engage in research independently.
・Understanding and evaluating other people's research.
・We will empower non-specialists in this field to explain clearly.
・To acquire the ability from data science perspective to solving problems.
While valuing our values, we are working hard toward empirical graduation research on understanding phenomena, problem solving, and value creation through data design (planning), collection, and analysis of data science (data science) approaches to various issues in research fields of interest.
The main pillars are "Human resources who can think of research from a statistical and data science perspective", "Basic research on statistical and data science methods", and "Applied research that can be utilized in the fields of natural and humanities and social sciences".

<FY2024 Graduate Studies> (Department of Economics)
Player performance and win/loss analysis by set count in the four major tennis tournaments
Analysis of shrinking scale and pursuing profits at Shinkin Banks
Analysis of factors affecting winning rates in the Japanese professional baseball world
Impact on industry, consumption, and number of spectators by the team ranking
Factor analysis of satisfaction in the Shimonoseki Sea Hibiki Marathon
Analysis on the solution of worries and worries of new students at Shimonoseki City University
Network analysis of the amount of flow between prefectures
The impact of collaborative exhibitions by "Token Ranbu" on the number of visitors
Consideration of factors when choosing a way to go to university
The Impact of Vertical Short Video Advertising on Consumers — For Shimonoseki City University Students―
About the female ratio of companies and international involvement
Effectiveness of the Arikaport Karato Area Master Plan to Increase Tourists
Subjective happiness from “health”, “education / education”, “income”, “family / marriage”, and “neighbor / community”
Analysis and countermeasures for elderly traffic accidents before and after COVID-19 in Yamaguchi Prefecture

<FY2023 Graduate Studies> (Department of Economics)
Impact of emission regulations on the second-hand motorcycle market and future prospects
Investment Environment Outlook Using Text Mining: Analysis of the Relationship between Reports and Stock Prices
Current status and future prospects of cashless payments
Potential of Lab-grown Diamonds in the Japanese Jewelry Industry
Consideration of the Relevance of Logistics Function and Minato Town Development
Analysis of the current situation of smart houses and future prospects from management strategy
Consideration on the development of the OTT platform in your own country: Focusing on the OTT platform in Korea

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