Clinical epidemiology, public health, biostatistics, health psychology, medical informatics, medical economics, mental health, medical policy, nursing management

April 2009 - March 2012 Ph.D. Program in Health Science and Nursing, Graduate School of Medicine, The University of Tokyo
April 2007 - March 2009 Master's degree in Health Science and Nursing, Graduate School of Medicine, The University of Tokyo
April 2000 - March 2005 Faculty of Nursing Nagoya City University

Ph.D. (Health Studies)
Master's (Health Studies)
Bachelor of Nursing

Japan Society of Clinical Epidemiology, Japan Society of Behavioral Medicine, Japan Society of Medical Information, Japan Society of Nursing Management, Japan Society of Nursing Science, Japan Society of Medical Policy

Mental health, real-world data, health economics, data science, organizational support, stress response, performance improvement, intervention strategy optimization

Empirical study to improve mental health and performance of workers
Policy recommendations and health economics research using real-world data
Multi-layered organizational support and empirical research on stress response and mental health effects of health workers
Healthcare outcomes forecasting and intervention strategy optimization research using data science
Applied research in the field of clinical epidemiology using statistical methods

[International Academic Journal (reviewed)]
[2025]
1) Kubota K, Aishima M, Fujita T. Harnessing Generative AI in Nursing Informatics: A Theoretical Critique and Policy Innovation Perspective From Japan. Int Nurs Rev. 2025 Sep; 72(3): e70108. doi: 10.1111/inr.70108.
2) Takeuchi S*, Kubota K*, Nakamura S. Artificial Intelligence and Tacit Knowledge Integration in Midwifery: Policy Implications for Improving Healthcare Outcomes. Int Nurs Rev. 2025 Sep; 72(3): e70092. doi: 10.1111/inr.70092. *Equal contributed
3) Ito H, Seki T, Kawazoe Y, Takiguchi T, Akagi Y, Kubota K, Miyake K, Okada M, Ohe K. Prognostic impact of the timing of antihypertensive medication initiation for hypertension detected at health screening on primary prevention of adverse cardiovascular events: Age-stratified real-world data analysis. Hypertens Res. 2025 Sep; 48(9): 2401-2412. doi: 10.1038/s41440-025-02249-1.
4) Seki T, Kawazoe Y, Takiguchi T, Akagi Y, Ito H, Kubota K, Miyake K, Okada M, Ohe K. Sex Differences in Post-Noncardiac Surgery Risks Assessed Using the Revised Cardiac Risk Index - A Nationwide Retrospective Cohort Study. Circ J. 2025 Aug 25;89(9): 1547-1554. doi: 10.1253/circj.CJ-24-0846.
5) Kubota K, Tsukamoto S, Sugawara J, Noritake R, Fujita T. Public Perception of Healthcare and the Potential of Generative AI in Japan: Findings from a Nationwide Survey. Stud Health Technol Inform. 2025 Aug 7;329:2088-2089. doi: 10.3233/SHTI251363.
6) Ito H, Seki T, Kawazoe Y, Takiguchi T, Akagi Y, Kubota K, Miyake K, Okada M, Ohe K. Evaluation of Perioperative Cardiovascular Event Risk in Gastrointestinal Surgery - Predictive Modeling and Risk Stratification Using Machine Learning. Circ J. 2025 Apr 24. doi: 10.1253/circj.CJ-25-0032.
7) Ogawara Y, Yokota NR, Yamada Y, Arakawa N, Sakamaki K, Kobayashi H, Kubota K, Kimura F, Mizushima T, Yamazaki E, Miyagi E. Assessment of tissue factor pathway inhibitor 2 (TFPI2) as a novel serum marker for malignant tumors of the ovary before and after treatment: A case-control study. J Obstet Gynaecol Res. 2025 Feb; 51(2): e16241. doi: 10.1111/jog.16241.

[2024]
1) Seki T, Takiguchi T, Akagi Y, Ito H, Kubota K, Miyake K, Okada M, Kawazoe Y. Iterative random forest-based identification of a novel population with high risk of complications post non-cardiac surgery. Sci Rep. 2024 Nov 5;14(1): 26741. doi: 10.1038/s41598-024-78482-4.
2) Fujimoto H, Iida M, Takeuchi S, Shinohara E, Kubota K, Nakamura S. Effects of an individualized nutritional educational program in pregnant women: A randomized controlled trial in Japan. Jpn J Nurs Sci. 2024 Jul; 21(3): e12599. doi: 10.1111/jjns.12599.
3) Harada F, Miyake K, Matsuyama R, Furuta K, Kida M, Ohkawa S, Tanaka JI, Asakura T, Sugimori K, Kawaguchi Y, Mine T, Kubota K, Shimada H, Endo I. Therapeutic Outcome of Multidisciplinary Treatment in Unresectable Biliary Tract Cancer: A Multicenter Retrospective Analysis. World J Oncol. 2024 Jun; 15(3): 405-413. doi: 10.14740/wjon1821.
4) Nagasawa S, Hirata Y, Miyamoto S, Ozono S, Iida S, Katano H, Tsuneya S, Kira K, Kobayashi S, Nakajima M, Abe H, Ikemura M, Yamamoto I, Nakagawa K, Kubota K, Akitomi S, Hasegawa I, Ushiku T, Suzuki T, Iwase H, Makino Y, Saitoh H. Changes in SARS-CoV-2 viral load and titers over time in SARS-CoV-2-infected human corpses. PLoS One. 2024 Mar 27;19(3): e0287068. doi: 10.1371/journal.pone.0287068.
5) Yoshizawa T, Makram AM, Elsheikh R, Nakamura S, Makram EM, Kubota K, Huy NT, Moji K. Spirituality, Quality of Life, and Health: A Japanese Cross-Sectional Study. Eur J Investig Health Psychol Educ. 2024 Mar 21;14(3): 767-781. doi: 10.3390/ejihpe14030050.
6) Kubota K, Seki T, Miyake K, Okada M, Nishio K, Ohe K. Providing Practical Knowledge and Skills to Handle Real-World Data? Lessons Learned from Med RWD Program. Stud Health Technol Inform. 2024 Jan 25;310:1540-1541. doi: 10.3233/SHTI231283.

※Please refer to researchmap for research results before 2023 (including Japanese-style academic journals (reviewed), MISC etc.).

1) The association between frequency of social interaction and mental health problems in the elderly: Cross-sectional research using JACSIS research data
Promotion of interdisciplinary research through collaboration between the Faculty of Shimonoseki City University June 2025 - March 2026
2) Development of assessment tools for prevention of cracks and injuries that pass on the practical knowledge of skilled midwives
Japan Society for the Promotion of Science Grant-in-Aid for Scientific Research (C) April 2023 - March 2026 (partner of research)
3) Study of postoperative sleep disturbance effect of melatonin/lamelteon administration
Japan Society for the Promotion of Science Grant-in-Aid for Scientific Research (C) April 2020 - March 2024 (Research Contributors)
4) Development of physical motion measurement in low birth weight infants and research related to infant weight and developmental indicators
Japan Society for the Promotion of Science Grant-in-Aid for Scientific Research (C) April 2020 - March 2023 (Research Contributors)
5) Research on gender differences among nurses in other countries (Research cooperator (Secretary Director))
Ministry of Health, Labour and Welfare Research October 2021 - May 2022
6) Public Health Nurse Midwifery Nurse Research on Computer Utilization in National Examinations
FY2022 Health and Welfare Labor Administration Promotion Survey Project Cost Subsidy (Research Project for Regional Medical Infrastructure Development) April 2022 - March 2023 (Research Contributors)
7) Research on the utilization of MID-NET in medical information database research by academics
National Institute for Medical Research and Development, Japan Agency for Medical Research and Development, Pharmaceuticals, etc., April 2018 - March 2021 (Research contributors)
8) Research on factors related to hospitalization and discharge of psychiatric hospitals for elderly people with dementia at home and how to support community life
Japan Society for the Promotion of Science (JSPS) Young Researchers (B) April 2014 - March 2017 (Research Contributors)
9) Survey of gaps in awareness and action regarding emergency requests by residents of non-medical districts
Emergency Research Grants for Emergency Relief Foundation 2013 - 2014 (Research Contributors)
10) Building a society with a wide range of bonds: Social platform research that enables community-based elderly care
2012 - 2014 (Research Representative)

[History of Committee Members]
September 2019 - August 2021 The 25th Annual Meeting of the Japanese Society for Nursing Management
April 2018 - March 2021 Technical Expert (Biostatistics) at the Clinical Research Review Committee of Yokohama City University
December 2015 - March 2020 Full-time peer review committee member in charge of statistics for Japanese Journal of Nursing Science, Japan
April 2017 - January 2020 Vice Chair of the Expert System Committee of the Japan Society for Clinical Epidemiology (Program Certification Team Leader)
February 2016 - August 2018 The 21st Annual Meeting of the Japanese Society for Nursing Management
January 2017 - Dec. 2017 Planning Committee Member of the 24th Annual Meeting of the Japanese Society of Behavioral Medicine
March 2025 - Member of the Japan Society for Medical Policy Coordination Committee
July 2025 – September 2025 Springer Nature’s Reviewer Communities Trusted Reviewer
October 2025 – Until now Springer Nature’s Reviewer Communities Reviewing Editor

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