A paper written by NAKAGAMI Yuki Faculty of Data Science and others (joint research with the Department of Gastroenterology and Oncology, Graduate School of Medicine, Yamaguchi University) was published in an international journal. It was published in an academic journal called Experimental and Therapeutic Medicine published by SPANDIDOS PUBLICATIONS.

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https://www.spandidos-publications.com/10.3892/etm.2024.12608

Information on thesis　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　

Magazine name: Experimental and Therapeutic Medicine

Thesis title: Risk factors for infectious complications after gastrectomy in older patients "risk factors for infectious complications after gastrectomy in older patients"

Author: MICHIHISA IIDA¹, SHIGERU TAKEDA¹, TSUNENORI YAMAMOTO¹, CHIYO NAKASHIMA¹, MITSUO NISHIYAMA¹, YUSAKU WATANABE¹, YOSHITARO SHINDO¹, YUKIO TOKUMITSU¹, SHINOBU TOMOCHIKA¹, YUKI NAKAGAMI², HIDENORI TAKAHASHI¹ and HIROAKI NAGANO¹

¹Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine

²Department of Data Science, Faculty of Data Science, Shimonoseki City University

Overview of Research　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　

Objective: Identify risk factors for preoperative and intraoperative infectious complications in older patients with gastric cancer.

"Method": We analyzed the risk factors of infectious complications based on the Clavien-Dindo classification based on statistical modeling and cross-confirmation from preoperative and intraoperative factors for 504 gastric cancer patients aged 65 and over who had radical gastrectomy.

"Results": Of the 504 patients, 95 (18.8%) had infectious complications. An analysis of preoperative factors alone showed that men and prognostic index values are low, visceral fat area values are high, and total gastrectomy is a risk factor for complications after gastrectomy. Among all intraoperative factors, low prognostic nutritional index and prolonged surgery was identified as a risk factor for complications after gastrectomy. Furthermore, when patients were divided into five groups according to the number of positive risk factors for preoperative infectious complications, the incidence of complications varies among groups.

"Conclusions": Elderly patients with gastric cancer have found that if there are many preoperative risk factors, it is necessary to carefully consider the indication of gastrectomy and reduce complications by reducing surgical time.

[Publishing date: 2024.07.03]